iolW [2017-05-11 10:38:50]

scyllo-inositol dehydrogenase, general stress protein

locus: BSU33530

pI: 5.46

mw: 39.95 kDa

protein length: 358 aa

gene length: 1074 bp

function: unknown

product: scyllo-inositol dehydrogenase

essential: no

synonyms: yvaA

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.16|Utilization of inositol]
• [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.1|General stress proteins (controlled by SigB)]

Gene

Coordinates: 3,444,329 → 3,445,405

The protein

Protein family

• gfo/idh/mocA family (according to Swiss-Prot)

Paralogous protein(s)

• [protein|03BE6DA854612B3F6741E0E167AB310F0DE96285|YfiI], [protein|29DAF5343A42EAD8DB97925FE7D049410F7B7FCA|NtdC], [protein|942BAE9FA023DFCA06B6D26A856A72F2979E23FA|YrbE], [protein|484D17480DFAD3667E0EBC6D38854A7546A8DB46|YteT], [protein|920C5750CB95102B073C32874D512E8D636D2C7D|IolU], [protein|93C1DF93CAFC5AE726523A91A3BA7470017FF6DC|IolG]

Structure

• [PDB|3GFG]

Expression and Regulation

Operons

• genes: [gene|7DFE74C751A67CCC84579D52005E1399B0A10166|iolW]
  description: [pubmed|22383849]

  sigma factors

  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|15805528], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]

  regulation

  • induced by stress ([protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]) [Pubmed|15805528]

Biological materials

Mutant

• MGNA-A443 (iolU::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/443 NBRP B. subtilis, Japan]

References

• 15805528,20133360,24325193